Morgado Carlos, Ruivo Nuno
Department of Neuroradiology, Hospital de Santa Maria, Universidade de Lisboa, Avenida Prof. Egas Moniz, 1649-035 Lisboa, Portugal.
Eur J Radiol. 2005 Aug;55(2):188-92. doi: 10.1016/j.ejrad.2005.04.017.
Tuberculosis is becoming an increasingly troublesome public health problem mostly because of incomplete therapy of existing cases giving rise to multi-drug resistant strains and because of increase in immunodeficiency states from various causes. The disease affects preferentially economically underprivileged individuals. In this paper, we review the pathogenesis and radiological findings of meningo-encephalic tuberculosis. Imaging manifestations are very pleomorphic and can mimic parenchymal cerebral mass lesions or meningeal processes of different nature. Although imaging findings are generally non-specific, modern imaging plays a key role in the diagnosis. A high index of suspicion in the appropriate clinical and laboratorial setting may promote rapid diagnosis and institution of therapeutic measures that avoid death or serious neurological consequences.
结核病正日益成为一个棘手的公共卫生问题,主要原因是现有病例治疗不彻底导致多药耐药菌株的产生,以及各种原因引起的免疫缺陷状态增加。该疾病主要影响经济上处于不利地位的人群。在本文中,我们回顾了脑膜脑型结核病的发病机制和影像学表现。影像学表现非常多样,可模仿实质性脑肿块病变或不同性质的脑膜病变。虽然影像学表现通常不具有特异性,但现代影像学在诊断中起着关键作用。在适当的临床和实验室环境中保持高度怀疑指数,可能有助于快速诊断并采取治疗措施,避免死亡或严重的神经后果。