Morello Frank A, Wright Kenneth C, Lembo Thomas M
Department of Interventional Radiology, University of Texas M. D. Anderson Cancer Center, Houston, Tex, USA.
Radiology. 2005 Jun;235(3):1045-9. doi: 10.1148/radiol.2353040433.
In an attempt to remove air that enters the pleural space during computed tomography (CT)-guided coaxial transthoracic needle biopsy, the authors fashioned an 18-gauge experimental suction guide needle and evaluated the incidence of pneumothorax with this needle in comparison to the incidence of pneumothorax with a standard 18-gauge guide needle in a canine model. This experiment had animal care and use committee approval. Ten dogs underwent a biopsy of each lung, for a total of 20 lung biopsies. Half of the biopsies were performed by using the experimental needle (five right lungs, five left lungs), and half were performed by using a standard guide needle. CT revealed pneumothorax during the procedure and was performed to reveal pneumothorax 1 and 3 hours after the procedure. A significant reduction (P < .016) in intraprocedural lung biopsy-associated pneumothorax was found when the experimental guide needle was used.
为了在计算机断层扫描（CT）引导下的同轴经胸针活检过程中排出进入胸膜腔的空气，作者制作了一根18号实验性抽吸引导针，并在犬模型中评估了使用该针时气胸的发生率，并与使用标准18号引导针时气胸的发生率进行比较。该实验获得了动物护理和使用委员会的批准。10只狗的每侧肺都接受了活检，总共进行了20次肺活检。一半的活检使用实验针进行（右肺5次，左肺5次），另一半使用标准引导针进行。CT在操作过程中显示气胸，并在操作后1小时和3小时进行以显示气胸。使用实验引导针时，术中与肺活检相关的气胸发生率显著降低（P < .016）。
