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对儿童进行免疫接种,以防范韩国青少年和年轻人中甲型肝炎风险的不断上升。

Immunizing children to protect against the increasing risk of hepatitis A in adolescents and young adults in South Korea.

作者信息

Sohn Y M, Lee J S, Park J H, Poerschke G, Eves K, Gress J, Kuter B

机构信息

Department of Pediatrics, Yongdong Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Southeast Asian J Trop Med Public Health. 2004 Dec;35(4):954-8.

PMID:15916097
Abstract

We evaluated the CR326F strain (VAQTA) derived hepatitis A vaccine in Korean children and adolescents >2 years of age to consider a future immunization program. In our study, the pediatric two-dose regimen of VAQTA was found to be generally well tolerated and resulted in 100% (95% CI 94.8, 100.0) seroconversion after 2 doses. Immunizing children with the HAV vaccine routinely should be considered in South Korea, particularly in areas where recent outbreaks have occurred.

摘要

我们在2岁以上的韩国儿童和青少年中评估了CR326F株(VAQTA)甲型肝炎疫苗,以考虑未来的免疫规划。在我们的研究中,发现VAQTA的儿科两剂方案总体耐受性良好,两剂后血清转化率达100%(95%CI 94.8, 100.0)。韩国应考虑对儿童常规接种甲型肝炎疫苗,特别是在近期发生过疫情的地区。

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Hum Vaccin Immunother. 2019;15(2):426-432. doi: 10.1080/21645515.2018.1530934. Epub 2018 Nov 15.
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