Belloni Fortina Anna, Piaserico Stefano, Zattra Edoardo, Alaibac Mauro
Melanoma Res. 2005 Jun;15(3):223-4. doi: 10.1097/00008390-200506000-00014.
The induction of multiple eruptive melanocytic naevi has frequently been reported to occur in association with chemotherapy or immunosuppressive regimens, particularly in children and adolescents. We describe the dermoscopic features of eruptive melanocytic naevi in an adult non-transplanted patient receiving immunosuppressive therapy for Crohn's disease. By dermoscopy, we observed a peripheral rim of large brown globules in most of the lesions. We have previously identified a group of patients characterized by this dermoscopic feature. These patients were children, adolescents and young adults with renal allografts receiving immunosuppressive therapy. The findings of our case strongly suggest that this dermoscopic feature may be associated with eruptive naevi developed in association with immunosuppression from any cause.
据报道，多发性发疹性黑素细胞痣的诱发常与化疗或免疫抑制方案有关，尤其是在儿童和青少年中。我们描述了一名成年非移植患者在接受克罗恩病免疫抑制治疗时出现的发疹性黑素细胞痣的皮肤镜特征。通过皮肤镜检查，我们在大多数皮损中观察到一个由大的褐色小球组成的周边边缘。我们之前已鉴定出一组具有这种皮肤镜特征的患者。这些患者是接受免疫抑制治疗的肾移植儿童、青少年和年轻成年人。我们病例的研究结果强烈提示，这种皮肤镜特征可能与因任何原因的免疫抑制而出现的发疹性痣有关。
