Blanc-Muesser M, Vigne L, Driguez H, Lehmann J, Steck J, Urbahns K
Centre de Recherches sur les Macromolecules Vegetales C.N.R.S., Grenoble, France.
Carbohydr Res. 1992 Feb 7;224:59-71. doi: 10.1016/0008-6215(92)84093-8.
The synthesis is reported of methyl 4,4'-dithio-alpha-maltotrioside (12) and the spacer-modified disaccharide glycosides methyl 4-S-(4-alpha-D-glucopyranosylthio-2-hydroxybutyl)-4-thio-alpha -D-glucopyranoside (20) and methyl 4-S-[(1,5/4,6)- and (4,6/1,5)-4-alpha-D-glucopyranosylthio-5,6-dihydroxy-2- cyclohexen-1-yl]-4-thio-alpha-D-glucopyranoside (29a/b), which are analogues of methyl alpha-maltotrioside. The Ki values for alpha-amylase for these compounds were determined as were those of methyl alpha-maltotrioside and maltose.
报道了4,4'-二硫代-α-麦芽三糖苷甲酯（12）以及间隔基修饰的二糖糖苷4-S-(4-α-D-吡喃葡萄糖硫基-2-羟基丁基)-4-硫代-α-D-吡喃葡萄糖苷甲酯（20）和4-S-[(1,5/4,6)-和(4,6/1,5)-4-α-D-吡喃葡萄糖硫基-5,6-二羟基-2-环己烯-1-基]-4-硫代-α-D-吡喃葡萄糖苷甲酯（29a/b）的合成，这些化合物是α-麦芽三糖苷甲酯的类似物。测定了这些化合物以及α-麦芽三糖苷甲酯和麦芽糖对α-淀粉酶的Ki值。
