Gao Jian, Woolley F Ross, Zingaro Ralph A
Department of Radiology, University of Texas Health Science Center-San Antonio, Texas 78229-3900, USA.
Org Biomol Chem. 2005 Jun 7;3(11):2126-8. doi: 10.1039/b503971a. Epub 2005 Apr 27.
Novel chiral Robson-type macrocyclic complexes M(2)-L [where M = Mn(II), Mn(III), Co(II) and Co(III) and L denotes tetra-Schiff base chiral ligands, L1 or L2] have been synthesized by metal template condensation of 2,6-diformyl-4-methyl-phenol, with 1R,2R-diaminocyclohexane (L1) or 1R,2R-diphenylethylenediamine (L2). The dinuclear Co(II) and Co(III) complexes catalyze asymmetric cyclopropanation of styrene with diazoacetate cooperatively and with high enantioselectivity.
新型手性罗布森型大环配合物M(2)-L [其中M = Mn(II)、Mn(III)、Co(II)和Co(III)，L表示四席夫碱手性配体L1或L2] 通过2,6-二甲酰基-4-甲基苯酚与1R,2R-二氨基环己烷（L1）或1R,2R-二苯基乙二胺（L2）的金属模板缩合反应合成。双核Co(II)和Co(III)配合物协同催化苯乙烯与重氮乙酸酯的不对称环丙烷化反应，且对映选择性高。
