[A control study of intravenous versus oral clomipramine in major depression].

Intravenous clomipramine (n = 105) and oral clomipramine (n = 64) were compared in a control study of 169 inpatients with major depression. The therapeutic effects were evaluated with four-degree scale and the rating scales of HDS and CGI. The results showed intravenous group has earlier response and better antidepressive effects than oral group within treatment period of 2 weeks. No significant differences between two groups were found in anticholinergic side-reaction. Clinical useful values of intravenous clomipramine were discussed.