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腹主动脉瘤筛查:建议与争议

Abdominal aortic aneurysm screening: recommendations and controversies.

作者信息

Longo Christopher, Upchurch Gilbert R

机构信息

Department of Surgery, Section of Vascular Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA.

出版信息

Vasc Endovascular Surg. 2005 May-Jun;39(3):213-9. doi: 10.1177/153857440503900301.

Abstract

Extensive level one evidence supports routine abdominal aortic aneurysm (AAA) screening in men aged 65 to 75 years, because AAAs are highly prevalent in this population. Physical examination is an insensitive means of detection. Ruptured AAAs are costly with respect to quality adjusted life years (QALY) lost and medical expenses. Large scale, randomized trials have demonstrated that AAA screening reduces all AAA-related mortality in the screened population and is cost-effective in mid-term follow-up. AAA screening by ultrasound has many advantages over other accepted medical screening programs in its simplicity in structure and the availability of an inexpensive, portable, and reliable means of screening. Additionally, AAA screening almost entirely avoids the negative consequences associated with other screening programs, including the adverse psychological effects and medical costs associated with false-positive examination results. There are subgroups of at-risk women who might benefit from AAA screening, and this issue should be further studied.

摘要

大量一级证据支持对65至75岁男性进行常规腹主动脉瘤(AAA)筛查,因为该人群中腹主动脉瘤非常普遍。体格检查是一种不敏感的检测手段。破裂的腹主动脉瘤在质量调整生命年(QALY)损失和医疗费用方面代价高昂。大规模随机试验表明,AAA筛查可降低筛查人群中所有与AAA相关的死亡率,并且在中期随访中具有成本效益。与其他公认的医学筛查项目相比,超声AAA筛查在结构上简单,且有廉价、便携和可靠的筛查手段,具有许多优势。此外,AAA筛查几乎完全避免了与其他筛查项目相关的负面后果,包括假阳性检查结果带来的不良心理影响和医疗费用。有一些高危女性亚组可能从AAA筛查中受益,这个问题应进一步研究。

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