根治性外阴切除术与改良根治性外阴切除术治疗外阴浸润性鳞状细胞癌的对比研究。

A comparative study of radical vulvectomy and modified radical vulvectomy for the treatment of invasive squamous cell carcinoma of the vulva.

作者信息

Hoffman M S, Roberts W S, Finan M A, Fiorica J V, Bryson S C, Ruffolo E H, Cavanagh D

机构信息

Department of Obstetrics and Gynecology, Tampa General Hospital, Florida.

出版信息

Gynecol Oncol. 1992 May;45(2):192-7. doi: 10.1016/0090-8258(92)90284-p.

DOI:10.1016/0090-8258(92)90284-p

PMID:1592286

Abstract

Forty-five patients who underwent a modified radical vulvectomy for invasive squamous cell carcinoma of the vulva were compared with forty-five patients who underwent radical vulvectomy for similar lesions. Vulvar wound infection and breakdown were infrequent in both groups. Anal incontinence developed postoperatively in five of the modified radical vulvectomy patients and in none of the radical vulvectomy patients. Urinary incontinence developed postoperatively in two of the modified radical vulvectomy patients and in seven of the radical vulvectomy patients. Possible reasons for these differences are discussed. One invasive local recurrence (2.2%) developed in the modified radical vulvectomy group and two (4.4%) local recurrences developed in the radical vulvectomy group. A modified radical vulvectomy appears to be efficacious for the vulvar phase of treatment of localized invasive squamous cell carcinoma of the vulva.

摘要

将45例行改良根治性外阴切除术治疗外阴浸润性鳞状细胞癌的患者与45例行根治性外阴切除术治疗类似病变的患者进行了比较。两组外阴伤口感染和裂开的情况均不常见。改良根治性外阴切除术组有5例患者术后出现肛门失禁，而根治性外阴切除术组无一例出现。改良根治性外阴切除术组有2例患者术后出现尿失禁，根治性外阴切除术组有7例出现。文中讨论了这些差异的可能原因。改良根治性外阴切除术组出现1例局部复发（2.2%），根治性外阴切除术组出现2例局部复发（4.4%）。改良根治性外阴切除术似乎对外阴局部浸润性鳞状细胞癌的外阴期治疗有效。