Ghezzi Fabio, Cromi Antonella, Bergamini Valentino, Raffaelli Ricciarda, Crotti Stefania, Segredini Raffaella, Bolis Pierfrancesco
Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy.
J Minim Invasive Gynecol. 2005 May-Jun;12(3):210-5. doi: 10.1016/j.jmig.2005.03.007.
To assess the impact of preemptive infiltration of port site with local anesthetic on postlaparoscopy pain.
Randomized, double-blind, controlled trial (Canadian Task Force classification I).
Two university hospitals.
A total of 170 women scheduled for gynecologic laparoscopic procedures were randomly assigned to pre-incisional infiltration with ropivacaine (n = 86) or with saline solution (n = 84).
Infiltration with either local anesthetic or placebo was accomplished in each port site before skin incision. All patients underwent standard anesthesia induction and maintenance.
Postoperative pain was evaluated with a visual analogue scale and patient interview at 1, 3, and 24 hours after surgery. No difference was found between groups in pain levels, pain location, or in the site of superficial pain at any of the postoperative time periods. The proportion of women requiring analgesia before discharge was similar in the local anesthetic group and in the saline group (22/86 [25.6%] vs 19/84 [22.6%], p = .72). The analgesic consumption in the first 24 hours after surgery and the time to first analgesic request did not differ significantly between the two groups.
Preemptive infiltration of trocar sites with ropivacaine is not effective in postoperative pain relief.
评估局部麻醉药对端口部位进行预先浸润对腹腔镜检查术后疼痛的影响。
随机、双盲、对照试验（加拿大工作组分类I）。
两家大学医院。
共有170名计划进行妇科腹腔镜手术的女性被随机分配接受罗哌卡因切口前浸润（n = 86）或生理盐水浸润（n = 84）。
在皮肤切口前对每个端口部位进行局部麻醉药或安慰剂浸润。所有患者均接受标准的麻醉诱导和维持。
术后1、3和24小时，通过视觉模拟评分法和患者访谈评估术后疼痛。在任何术后时间段，两组在疼痛程度、疼痛部位或浅表疼痛部位方面均未发现差异。局部麻醉药组和生理盐水组中出院前需要镇痛的女性比例相似（22/86 [25.6%] 对19/84 [22.6%]，p = 0.72）。两组术后24小时内的镇痛药消耗量以及首次要求镇痛的时间无显著差异。
罗哌卡因对套管针部位进行预先浸润在缓解术后疼痛方面无效。
