Peng Yan-Zhen, Shen Keng, Wu Ming, Huang Hui-Fang, Pan Ling-Ya, Yang Jia-Xin, Lang Jing-He
Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Fu Chan Ke Za Zhi. 2005 Apr;40(4):243-5.
To study the differences of clinical characteristics between patients with extraovarian peritoneal serous papillary carcinoma (EPSPC) and those with papillary serous ovarian carcinoma (PSOC).
Fourteen patients with EPSPC and 50 patients with PSOC who were admitted to Peking Union Medical College Hospital from 1984 to 2002 were retrospectively analyzed, and their clinical features, chemosensitivities and survival rate were compared.
Patients with EPSPC were significantly older than those with PSOC (mean age 62.7 years versus 53.6 years, P < 0.01). The chemo-resistant rate (83%) in EPSPC was significantly higher than that (38%) of the PSOC (P < 0.05). The 1-, 2-, and 3-year survival rates (72%, 10%, 0%) in the EPSPC were significantly lower than those (95%, 79%, 62%) of the PSOC (P < 0.05).
EPSPC are likely to occur in older women, have higher chemo-resistance and poorer prognosis compared with PSOC.
研究卵巢外腹膜浆液性乳头状癌（EPSPC）患者与浆液性乳头状卵巢癌（PSOC）患者临床特征的差异。
回顾性分析1984年至2002年在北京协和医院收治的14例EPSPC患者和50例PSOC患者，比较其临床特征、化疗敏感性和生存率。
EPSPC患者的年龄显著大于PSOC患者（平均年龄62.7岁对53.6岁，P<0.01）。EPSPC的化疗耐药率（83%）显著高于PSOC（38%）（P<0.05）。EPSPC的1年、2年和3年生存率（72%、10%、0%）显著低于PSOC（95%、79%、62%）（P<0.05）。
与PSOC相比，EPSPC可能发生于老年女性，具有更高的化疗耐药性和更差的预后。
