Zappia J J, McClatchey K D
Department of Otolaryngology, University of Michigan, Ann Arbor 48109.
Int J Pediatr Otorhinolaryngol. 1992 Jan;23(1):85-9. doi: 10.1016/0165-5876(92)90083-2.
As treatment and survival of acute leukemia as well as other types of pediatric cancer improve, the number of second malignancies in these treated patients will increase. Occurrence of these second malignancies in the head and neck is not frequently reported although it is known that radiation treatment, chemotherapy and sometimes the primary lesion itself are risk factors for neoplasia. Malignancies of the parotid gland in the pediatric population are known to be unusual. We discuss a mucoepidermoid carcinoma in a 10-year-old female who 7 years earlier had undergone successful treatment of acute lymphoblastic leukemia.
随着急性白血病以及其他类型儿童癌症的治疗方法改进和生存率提高,这些接受治疗的患者中出现第二原发恶性肿瘤的数量将会增加。尽管已知放射治疗、化疗,有时原发肿瘤本身就是肿瘤形成的危险因素,但头颈部出现这些第二原发恶性肿瘤的情况却鲜有报道。小儿腮腺恶性肿瘤较为罕见。我们讨论了一名10岁女性的黏液表皮样癌,该患者7年前曾成功治愈急性淋巴细胞白血病。