Chisin R, Noyek A M, Israel O, Witterick I J, Front D, Kirsh J C
Department of Medical Biophysics and Nuclear Medicine, Hadassah University Hospital, Jerusalem, Israel.
Isr J Med Sci. 1992 Mar-Apr;28(3-4):254-61.
Nuclear medicine contributes to the diagnosis and management of extracranial head and neck diseases through the physiological information it provides. In addition to thyroid and parathyroid indications, radionuclide studies, i.e., bone and 67Gallium citrate scans are helpful in diagnosing and treating head and neck malignancies. Positron emission tomography with 18F-fluorodeoxy-glucose evaluates tumor glucose metabolism before and after treatment. Triphase bone scintigraphy enables early detection of osteomyelitis of the skull base, and its management requires 67Gallium-citrate or 111Indium-WBC scintigraphies. Salivary gland scintigraphy is the only functional imaging test of salivary tissue and should be utilized more in the diagnosis of submandibular duct obstruction and in the evaluation of preserved parenchymal function after recurrent infections.
核医学通过提供生理信息，为颅外头颈部疾病的诊断和管理做出贡献。除了甲状腺和甲状旁腺适应症外，放射性核素研究，即骨扫描和枸橼酸镓扫描，有助于诊断和治疗头颈部恶性肿瘤。18F-氟脱氧葡萄糖正电子发射断层扫描可评估治疗前后肿瘤的葡萄糖代谢情况。三相骨闪烁显像能够早期发现颅底骨髓炎，其治疗需要枸橼酸镓或铟-111白细胞闪烁显像。唾液腺闪烁显像是唾液组织唯一的功能成像检查，在诊断下颌下腺导管阻塞以及评估反复感染后实质功能保留情况方面应更多地加以利用。
