Singh T N, Kananbala S, Devi K S
Department of Microbiology, Regional Institute of Medical Sciences, Lamphelpat - 795 004, India.
Indian J Med Microbiol. 2005 Apr;23(2):131-4. doi: 10.4103/0255-0857.16056.
Paragonimiasis is an important cause of pulmonary disease worldwide. Infection in humans mainly occurs by ingestion of raw or undercooked freshwater crabs or crayfish. The disease is well known in endemic regions of Asian countries, where culturally based methods of food preparation foster human transmission. Three patients with clinical and radiological features compatible with pulmonary tuberculosis had been treated for tuberculosis without remedy despite an inability to demonstrate acid fast bacilli in sputum smears. All patients had history of ingestion of raw crabs and crayfish. The confirmed diagnosis of pleuropulmonary paragonimiasis was made based on the demonstration of Paragonimus eggs in the sputum, and high absolute eosinophilia in their peripheral blood and pleural fluid. All the patients had been treated with praziquantel successfully.
肺吸虫病是全球肺部疾病的一个重要病因。人类感染主要通过食用生的或未煮熟的淡水蟹或小龙虾。在亚洲国家的流行地区，这种疾病广为人知，当地基于文化的食物制备方法助长了人际传播。三名具有与肺结核相符的临床和放射学特征的患者，尽管痰涂片未发现抗酸杆菌，但接受了肺结核治疗却未见好转。所有患者都有食用生蟹和小龙虾的病史。根据痰中发现肺吸虫卵、外周血和胸腔积液中嗜酸性粒细胞绝对值升高，确诊为胸膜肺吸虫病。所有患者均接受吡喹酮治疗并成功治愈。
