Lee Yoon-Jung, Kim Joon-Hyun, Ko Myung-Kyoo
Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2005 Mar;19(1):34-9. doi: 10.3341/kjo.2005.19.1.34.
The aim of this study is to elucidate the association of neovascularization in branch retinal vein occlusion (BRVO) combined with major arterial insufficiency (MAI), compared with BRVO alone. The authors retrospectively reviewed the charts, color photographs, and fluorescein angiograms of 304 patients (308 eyes) who had BRVO from 1990 to 2002 at Hanyang University hospital. Patients with BRVO combined with MAI and patients with BRVO alone were differentiated by angiographic appearance. Of the 308 eyes, 12 (3.9%) had neovascularization, all of which were in the 56 eyes of the MAI group for which the neovascularization rate was 21.4%. Neovascularization in BRVO was more strongly associated with the non-perfusion caused by MAI, rather than with the extent of the non-perfusion area that originated from retinal capillary obstruction. MAI is considered as a risk factor for neovascularization and hence could be a prognostic factor.
本研究旨在阐明视网膜分支静脉阻塞（BRVO）合并严重动脉供血不足（MAI）时新生血管形成的情况，并与单纯BRVO进行比较。作者回顾性分析了1990年至2002年在汉阳大学医院就诊的304例（308只眼）BRVO患者的病历、彩色照片和荧光素血管造影。通过血管造影表现区分BRVO合并MAI的患者和单纯BRVO的患者。在308只眼中，12只（3.9%）出现新生血管，均在MAI组的56只眼中，其新生血管形成率为21.4%。BRVO中的新生血管形成与MAI导致的无灌注关系更为密切，而非与视网膜毛细血管阻塞引起的无灌注区域范围相关。MAI被认为是新生血管形成的一个危险因素，因此可能是一个预后因素。
