Choi Myung Geun, Han Min, Kim Young Il, Lee Joo Haw
Department of Ophthalmology, Inje University Busan Paik Hospital, Busan, Korea.
Korean J Ophthalmol. 2005 Mar;19(1):40-6. doi: 10.3341/kjo.2005.19.1.40.
This study was performed to evaluate optic disc appearance, retinal nerve fiber layer (RNFL) thickness, and macular thickness in normal, ocular hypertensive (OHT) and glaucomatous eyes using optical coherence tomography (OCT) 3000. One hundred fifty-eight eyes of 167 consecutive subjects were enrolled: 60 normal, 53 OHT, and 54 glaucomatous. OCT topographic parameters of cup diameter, cup area, rim area, and cup/disc area ratio were significantly less in OHT eyes than in normal eyes and were significantly less in glaucomatous eyes than in normal and OHT eyes. RNFL was significantly thinner in OHT eyes than in normal eyes in the inferior quadrant, and in glaucomatous eyes than in OHT and normal eyes in the mean and for all four quadrants. Macular thickness was significantly thinner in glaucomatous eyes than in OHT and normal eyes throughout all subdivisions. Optic disc parameters, and RNFL and macular thickness measurements made with OCT may be useful in the clinical assessment of glaucoma.
本研究旨在使用光学相干断层扫描（OCT）3000评估正常眼、高眼压（OHT）眼和青光眼眼中视盘外观、视网膜神经纤维层（RNFL）厚度和黄斑厚度。连续纳入167名受试者的158只眼：60只正常眼、53只高眼压眼和54只青光眼眼。OCT测量的杯盘直径、杯盘面积、视盘边缘面积和杯盘面积比等地形学参数在高眼压眼中显著低于正常眼，在青光眼眼中显著低于正常眼和高眼压眼。RNFL在高眼压眼的下方象限显著薄于正常眼，在青光眼眼中的平均值以及所有四个象限均显著薄于高眼压眼和正常眼。在所有细分区域中，青光眼眼的黄斑厚度均显著薄于高眼压眼和正常眼。OCT测量的视盘参数以及RNFL和黄斑厚度可能有助于青光眼的临床评估。
