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猫眼外肌手术退缩或切除术后肌腱神经末梢的超微结构变化

Ultrastructural changes of myotendinous nerve endings following recession or resection procedures of extraocular muscle surgeries in cats.

作者信息

Kim Seunghyun, Cho Yoonae A

机构信息

Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.

出版信息

Korean J Ophthalmol. 2005 Mar;19(1):47-54. doi: 10.3341/kjo.2005.19.1.47.

DOI:10.3341/kjo.2005.19.1.47
PMID:15929487
Abstract

To verify the postoperative ultrastructural changes of the myotendinous nerve endings of feline extraocular muscles, which are known as proprioceptors. Sixteen recti of four cats were used and divided into three groups. In group A, eight lateral recti were recessed. In group B, four medial recti were resected by 10 mm from insertion to include the myotendinous junction. In group C, four medial recti were resected by 4 mm of muscle bellies only, without disturbing the myotendinous junction. Four weeks after surgery, specimens were examined with electron microscopy. In group A, overall neural structures were well maintained with slight axonal degeneration. In group B, only muscle fibers were observed without any regeneration of neural sprouts. In group C, axonal disintegration and shrinkage were evident. These results indicate that myotendinous nerve endings can be damaged in strabismus surgery, and that resection was more invasive than recession in disrupting myotendinous nerve endings.

摘要

为了验证猫眼外肌肌-腱神经末梢(即本体感受器)的术后超微结构变化。使用了4只猫的16条直肌,并将其分为三组。A组,8条外直肌进行后徙。B组,4条内直肌从附着点处切除10毫米,包括肌-腱连接部。C组,4条内直肌仅切除4毫米的肌腹,不干扰肌-腱连接部。术后4周,用电子显微镜检查标本。A组,整体神经结构保持良好,有轻微轴突退变。B组,仅观察到肌纤维,未见神经芽再生。C组,轴突崩解和萎缩明显。这些结果表明,斜视手术中肌-腱神经末梢可能受损,并且在破坏肌-腱神经末梢方面,切除比后徙的侵袭性更大。

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引用本文的文献

1
Ultrastructural changes in myotendinous nerve endings induced by injection of botulinum toxin into the extraocular muscle.注射肉毒毒素至眼外肌引起肌腱神经末梢的超微结构改变。
Graefes Arch Clin Exp Ophthalmol. 2010 Dec;248(12):1795-801. doi: 10.1007/s00417-010-1513-8. Epub 2010 Sep 17.