Psychophysiological reactions of patients with atopic dermatitis.

In a laboratory experiment, 20 female patients with atopic dermatitis (AD) and 20 female controls were exposed to two stress situations (watching a film about scarifications and tatooing, mental arithmetic). Recordings were made of systolic blood pressure, diastolic blood pressure, heart rate, skin conductance level (SCL), number of spontaneous (non-specific) electrodermal fluctuations (SF) and the PSI, the number of active palmar sweat glands in an area of the finger pad. Neither in the cardiovascular variables nor the PSI were any significant group differences found, neither for baseline nor stress values, nor for the response reactions. Atopic dermatitis persons had significantly lower values for SCL and SF throughout the whole experiment, although response reactions did not differ between groups. This study lends no support to the assumption of a general psychophysiological overreactivity or individual specific reactions of the skin system in patients with AD.