Hyslop W Brian, Balci N Cem, Semelka Richard C
Department of Radiology, University of North Carolina, 101 Manning Drive, CB #7510, Chapel Hill, NC 27599-7510, USA.
Magn Reson Imaging Clin N Am. 2005 May;13(2):211-24. doi: 10.1016/j.mric.2005.03.011.
In this article, we defined the major areas of active research in clinical MR imaging. Further increases in the number of parallel coils within an imaging array and in advances in parallel imaging pulse sequences and postprocessing will lead to further reductions in imaging time analogous to the impact of multidetector CT on helical CT. The synergism between parallel and high-field imaging will aid the development of high-field imaging. The combined dynamic and hepatic parenchymal enhancement of new contrast agents that have or may soon receive FDA approval will enable improved detection and characterization of liver lesions. The lymphotropic SPIO agents will remain an active area of clinical research to further assess their role in oncologic staging. Molecular imaging contrast research using magnetic particles and MR microscopy will continue to flourish. Screening examinations by MR imaging will re-main an area of research for the short- and intermediate term, with the final outcome dependent more on socioeconomic costs than the underlying capability of achieving high-quality screening studies.
在本文中，我们定义了临床磁共振成像（MR成像）中活跃的主要研究领域。成像阵列中并行线圈数量的进一步增加以及并行成像脉冲序列和后处理技术的进步，将导致成像时间进一步缩短，类似于多排探测器CT对螺旋CT的影响。并行成像与高场成像之间的协同作用将有助于高场成像的发展。已获得或可能很快获得美国食品药品监督管理局（FDA）批准的新型造影剂的动态和肝实质增强联合应用，将能够改善肝脏病变的检测和特征描述。亲淋巴超顺磁性氧化铁（SPIO）制剂仍将是临床研究的一个活跃领域，以进一步评估它们在肿瘤分期中的作用。使用磁性颗粒和MR显微镜的分子成像造影研究将继续蓬勃发展。MR成像筛查检查在短期和中期仍将是一个研究领域，最终结果更多地取决于社会经济成本，而非实现高质量筛查研究的潜在能力。
