Liepelt Steffen, Freund Jan A, Schimansky-Geier Lutz, Neiman Alexander, Russell David F
Institute of Physics, Humboldt-University Berlin, Newtonstr. 15, D-12489 Berlin, Germany.
J Theor Biol. 2005 Nov 7;237(1):30-40. doi: 10.1016/j.jtbi.2005.03.029.
Processing of external stimuli by sensory neurons often involves bursting, when epochs of fast firing alternate with intervals of quiescence. In particular, sensory neurons of electroreceptors in paddlefish (Polyodon spathula) undergo bursting when stimulated externally with broad-band noise, but otherwise fire spontaneously in a quasiperiodic tonic manner. We use a simple phenomenological model for noise-induced bursting to quantify analytically, by means of the Kullback entropy and Fisher information, the gain in information transfer and electroreceptor sensitivity for external noisy stimuli. A good agreement between theoretical predictions, numerical simulations and experimental data is shown.
感觉神经元对外部刺激的处理通常涉及爆发式放电，即快速放电阶段与静息间隔交替出现。特别是，匙吻鲟（Polyodon spathula）电感受器的感觉神经元在受到宽带噪声外部刺激时会发生爆发式放电，但在其他情况下以准周期性的紧张性方式自发放电。我们使用一个简单的噪声诱导爆发现象学模型，通过库尔贝克熵和费舍尔信息进行分析量化，以确定外部噪声刺激下信息传递的增益和电感受器的敏感性。结果表明理论预测、数值模拟和实验数据之间具有良好的一致性。
