Tammela T L, Hellström P A, Mattila S I, Ottelin P J, Malinen L J, Mäkäräinen H P
Division of Urology, Oulu University Central Hospital, Finland.
J Urol. 1992 Jun;147(6):1551-3. doi: 10.1016/s0022-5347(17)37623-1.
Sclerotherapy with 5% ethanolamine oleate was used to treat 102 hydroceles in 100 patients and 63 spermatoceles in 58 patients. Scrotal ultrasound examination was performed before the sclerotherapy and at each followup visit. Of the hydroceles 98% were cured completely and 68% were cured after only 1 sclerosant instillation, while 60% of the spermatoceles resolved completely and 33% partially, with 7% failures. No hydroceles recurred during an average followup of 43 months, whereas spermatocele recurred in 4 patients more than 1 year after successful treatment, with a mean followup of 46 months. Approximately half of the patients experienced pain after treatment, 3 had infection and 2 had hematoma. No changes in the structure or size of the testicles were found by ultrasound during followup. Ethanolamine oleate sclerotherapy is a safe, effective and economical form of outpatient therapy that can be recommended as primary treatment for hydroceles in adults and as an alternative to surgery for spermatoceles with 1 to 3 cysts in elderly men in whom fertility is not important.
采用5%油酸乙醇胺硬化疗法治疗100例患者的102例鞘膜积液及58例患者的63例精液囊肿。硬化疗法前及每次随访时均进行阴囊超声检查。鞘膜积液中98%完全治愈，68%仅注射1次硬化剂即治愈；而精液囊肿60%完全消退，33%部分消退，7%治疗失败。平均随访43个月期间，鞘膜积液无复发，而精液囊肿在成功治疗1年多后有4例复发，平均随访46个月。约一半患者治疗后出现疼痛，3例发生感染，2例出现血肿。随访期间超声检查未发现睾丸结构或大小改变。油酸乙醇胺硬化疗法是一种安全、有效且经济的门诊治疗方式，可推荐作为成人鞘膜积液的主要治疗方法，以及对生育不重要的老年男性1至3个囊肿的精液囊肿作为手术替代方案。
