Demina A B, Radenska-Lopovok S G, Folomeeva O M, Erdes Sh
Ter Arkh. 2005;77(4):77-82.
To study causes of death of rheumatic patients in Moscow.
Autopsy protocols for 1999-2002 were analysed for two pathoanatomic departments of Moscow.
Rheumatic diseases were detected in 165 cases (2.0% of overall number of autopsies in these departments). Rheumatic heart disease (RHD) was stated in 99 (60.0%) cases, rheumatic fever relapse (RFR) in 4 (2.4%), rheumatoid arthritis (RA) in 28 (17.0%), systemic lupus erythematosus (SLE) in 8 (4.8%), systemic sclerosis (SS) in 3 (1.8%), ankylosing spondilarthritis (AS) in 2 (1.2%), systemic vasculitis (SV) in 2 (1.2%), osteoarthrosis in 11 (7.3%), gout in 3 (1.8%), polymyositis in 1 (0.6%). RHD patients died of decompensated circulation (DC) (54%), acute heart failure (AHF) (14%), thromboembolism (TE) (6%), other causes (26%). RF patients died of TE (n = 2), DC (n = 1), AHF (n = 1). Out of 28 RA patients, 5 patients died of secondary amyloidosis, 3 of DC, 7 of AHF, 1 of TE, 5 of infectious complications, 7 of other causes. SLE patients died of uremia (n = 2), acute adrenal failure (n = 1), infectious complications (n = 2), AHF (n = 2), brain edema (n = 1).
Among rheumatic diseases, rheumatic heart valve disease was most severe as it caused the highest mortality. Cardiovascular pathology caused death in most of the rheumatic patients.
研究莫斯科地区风湿性疾病患者的死亡原因。
对莫斯科两个病理解剖科室1999 - 2002年的尸检记录进行分析。
共检测出165例风湿性疾病患者（占这些科室尸检总数的2.0%）。其中风湿性心脏病（RHD）99例（60.0%），风湿热复发（RFR）4例（2.4%），类风湿关节炎（RA）28例（17.0%），系统性红斑狼疮（SLE）8例（4.8%），系统性硬化症（SS）3例（1.8%），强直性脊柱炎（AS）2例（1.2%），系统性血管炎（SV）2例（1.2%），骨关节炎11例（7.3%），痛风3例（1.8%），多发性肌炎1例（0.6%）。风湿性心脏病患者死于循环代偿失调（DC）（54%）、急性心力衰竭（AHF）（14%）、血栓栓塞（TE）（6%）、其他原因（26%）。风湿热复发患者死于血栓栓塞（2例）、循环代偿失调（1例）、急性心力衰竭（1例）。28例类风湿关节炎患者中，5例死于继发性淀粉样变性，3例死于循环代偿失调，7例死于急性心力衰竭，1例死于血栓栓塞，5例死于感染性并发症，7例死于其他原因。系统性红斑狼疮患者死于尿毒症（2例）、急性肾上腺功能衰竭（1例）、感染性并发症（2例）、急性心力衰竭（2例）、脑水肿（1例）。
在风湿性疾病中，风湿性心脏瓣膜病最为严重，死亡率最高。大多数风湿性疾病患者死于心血管病变。
