Baysal Tamer, Oran Bülent, Başpinar Osman, Doğan Mustafa, Karaaslan Sevim
Section of Pediatric Cardiology, Department of Pediatrics, Meram Medical Faculty, Selçuk University, Konya, Turkey.
Anadolu Kardiyol Derg. 2005 Jun;5(2):112-5.
The aim of this study is to investigate prospectively whether intracardiac catheterization produces myocardial damage in paediatric heart.
The study was performed in all patients undergoing diagnostic cardiac catheterization at our institute. A baseline serum sample was drawn before the procedure. The second serum sample was obtained 4-6 hours after the procedure. Cardiac troponin-I and creatine kinase isoenzyme MB fraction levels were determined quantitatively.
Diagnostic cardiac catheterization was performed in 30 patients. There were 17 males and 13 females in the study group. The median age was 12 months (range 1 to 204 months); the median body weight was 8 kilograms (range 2.1 to 45 kilograms). The increase in cardiac troponin I (0.21+/-0.04 ng/ml to 1.16+/-1.40 ng/ml, p<0.05) and creatine kinase isoenzyme MB (26.68+/-7.53 U/L to 41.65+/-22.12 U/L, p< 0.05) levels after the procedure was significant.
This study shows that serum elevations of cardiac troponin I and creatine kinase isoenzyme MB occur after the most of paediatric diagnostic cardiac catheterization procedures.
本研究旨在前瞻性地调查心内导管插入术是否会对小儿心脏造成心肌损伤。
本研究在我院所有接受诊断性心导管插入术的患者中进行。在手术前采集一份基线血清样本。在手术后4 - 6小时采集第二份血清样本。定量测定心肌肌钙蛋白I和肌酸激酶同工酶MB水平。
30例患者接受了诊断性心导管插入术。研究组中有17名男性和13名女性。中位年龄为12个月（范围1至204个月）；中位体重为8千克（范围2.1至45千克）。术后心肌肌钙蛋白I水平（从0.21±0.04 ng/ml升至1.16±1.40 ng/ml，p<0.05）和肌酸激酶同工酶MB水平（从26.68±7.53 U/L升至41.65±22.12 U/L，p<0.05）的升高具有显著性。
本研究表明，大多数小儿诊断性心导管插入术后血清中心肌肌钙蛋白I和肌酸激酶同工酶MB水平会升高。
