Zhu Wenwei, Zhu Wenbiao, Zhang Wenhong, Han Fengchan, Dong Xiuzhen, Yan Xiaojun
Institute of Genetic Diagnosis, The Fourth Military Medical University, Xi'an 710032, PR China.
Biomed Microdevices. 2005 Jun;7(2):157-60. doi: 10.1007/s10544-005-1597-9.
To solve the problems existing in passive biochip systems, we designed a novel active biochip system. This system introduces negative pressure and controlling devices to adjust the antigen-antibody reaction on the nitrocellulose membrane. Computational simulation demonstrated that this system is a rapid, stable, robust and practical system that may enhance the efficiency of antigen-antibody reactions and improve the repeatability and accuracy of biochip analysis.
为了解决被动生物芯片系统中存在的问题，我们设计了一种新型的主动生物芯片系统。该系统引入了负压和控制装置，以调节硝酸纤维素膜上的抗原-抗体反应。计算模拟表明，该系统是一种快速、稳定、可靠且实用的系统，可提高抗原-抗体反应的效率，并提高生物芯片分析的重复性和准确性。
