有源生物芯片系统的设计与仿真
Design and simulation of active biochip system.
作者信息
Zhu Wenwei, Zhu Wenbiao, Zhang Wenhong, Han Fengchan, Dong Xiuzhen, Yan Xiaojun
机构信息
Institute of Genetic Diagnosis, The Fourth Military Medical University, Xi'an 710032, PR China.
出版信息
Biomed Microdevices. 2005 Jun;7(2):157-60. doi: 10.1007/s10544-005-1597-9.
To solve the problems existing in passive biochip systems, we designed a novel active biochip system. This system introduces negative pressure and controlling devices to adjust the antigen-antibody reaction on the nitrocellulose membrane. Computational simulation demonstrated that this system is a rapid, stable, robust and practical system that may enhance the efficiency of antigen-antibody reactions and improve the repeatability and accuracy of biochip analysis.
为了解决被动生物芯片系统中存在的问题，我们设计了一种新型的主动生物芯片系统。该系统引入了负压和控制装置，以调节硝酸纤维素膜上的抗原-抗体反应。计算模拟表明，该系统是一种快速、稳定、可靠且实用的系统，可提高抗原-抗体反应的效率，并提高生物芯片分析的重复性和准确性。
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