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[伴有广泛脂肪成分的小唾液腺梭形细胞肌上皮瘤报告]

[Report of a spindle cell myoepithelialioma of the minor salivary glands with extensive lipomatous component].

作者信息

Kern M A, Kasper H U, Drebber U, Guntinas-Lichius O, Veelken F, Ortmann M

机构信息

Zentrum für Pathologie der Universität zu Köln.

出版信息

Laryngorhinootologie. 2005 Jun;84(6):432-5. doi: 10.1055/s-2004-826218.

Abstract

Myoepitheliomas of the salivary glands are rare benign tumors composed of spindle-shaped myoepithelial cells, but may show plasmacytoid, epitheloid and clear cell-types that principally exhibit myoepithelial but not ductal differentiation. These tumors are mainly located in the major salivary glands and have sometimes abundant, acellular, mucoid or hyaline stroma but lack chondroid and myxochondroid foci, probably representing the one end of the spectrum of pleomorphic adenoma. Lipomatosis in the form of isolated small islands or scattered single lipocytes, is quite uncommon, and a large amount of adipose tissue in a pleomorphic adenoma and myoepithelioma is a rarity and only described in major salivary glands. We present the case report of a 38-year old man with a myoepithelioma of the minor palatinal salivary glands with extensive lipomatosis as an example of this rare phenomena.

摘要

涎腺肌上皮瘤是由梭形肌上皮细胞组成的罕见良性肿瘤,但可能表现为浆细胞样、上皮样和透明细胞型,主要显示肌上皮分化而非导管分化。这些肿瘤主要位于大涎腺,有时有丰富的无细胞黏液样或透明样间质,但缺乏软骨样和黏液软骨样灶,可能代表多形性腺瘤谱系的一端。以孤立的小岛状或散在的单个脂肪细胞形式存在的脂肪瘤病相当少见,多形性腺瘤和肌上皮瘤中大量脂肪组织则很罕见,仅在大涎腺中有描述。我们报告一例38岁男性腭部小涎腺肌上皮瘤伴广泛脂肪瘤病的病例,以此为例说明这种罕见现象。

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