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[1973 - 1987年巴登 - 符腾堡州多发性硬化症死亡率与社会地理变量的比较]

[Multiple sclerosis mortality 1973-1987 in Baden-Württemberg in comparison with socio-geographical variables].

作者信息

Lauer K, Firnhaber W

机构信息

Neurologische Klinik, Städtischen Kliniken, Darmstadt.

出版信息

Nervenarzt. 1992 Apr;63(4):209-12.

PMID:1594085
Abstract

Mortality due to MS in the State of Baden-Württemberg (south-west Germany) during the years 1973-1987 was studied in its geographical distribution for a possible association with selected sociogeographic indices for that period. The overall rate for Baden-Württemberg (1.3/100,000) was lower than in the neighbouring state of Hesse (1.5/100,000). A relative excess of cases was found in the highland region of the Swabian Alps. In multivariate analysis, correlations were found with the characteristics "forest area/inhabitant", "oat cultivation" and "concentration of polyaromatic hydrocarbons in the drinking water", whereas climate and height above sea-level were not associated. These findings require replication elsewhere.

摘要

对1973年至1987年间德国西南部巴登 - 符腾堡州因多发性硬化症(MS)导致的死亡率进行了研究,分析其地理分布情况,以探寻与该时期选定的社会地理指标之间可能存在的关联。巴登 - 符腾堡州的总体死亡率(1.3/100,000)低于邻国黑森州(1.5/100,000)。在施瓦本阿尔卑斯山的高地地区发现病例相对较多。在多变量分析中,发现与“森林面积/居民”、“燕麦种植”和“饮用水中多环芳烃浓度”等特征存在相关性,而与气候和海拔高度无关。这些研究结果需要在其他地方进行重复验证。

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