色素性紫癜性皮病与肝功能检查：10例患者报告
Pigmented purpuric dermatosis and hepatitis profile: a report on 10 patients.
作者信息
Dessoukey M Wagdy, Abdel-Dayem Hussein, Omar Mohamed F, Al-Suweidi Naeema E
机构信息
Department of Dermatology, Al-Jazeera Hospital, Abu Dhabi, United Arab Emirates.
出版信息
Int J Dermatol. 2005 Jun;44(6):486-8. doi: 10.1111/j.1365-4632.2005.02045.x.
BACKGROUND
Pigmented purpuric dermatosis comprises a group of vascular disorders of unknown etiology. Histologically, it is characterized by lymphocytic capillaritis in the papillary dermis. Although leukocytoclastic vasculitis confined to the skin is frequently reported with hepatitis C, lymphocytic vasculitis is rarely reported.
METHODS
Ten patients with pigmented purpuric dermatosis were studied clinically and histopathologically. Hepatitis profile was carried out in all of the patients to evaluate the possible relation.
RESULTS
Of the 10 patients, five tested positive for hepatitis C and two for hepatitis B antibodies.
CONCLUSION
Hepatitis C and B virus may play a role in the pathogenesis of pigmented purpuric dermatosis. Further case-control studies are necessary to confirm this conclusion.
背景
色素性紫癜性皮病是一组病因不明的血管疾病。组织学上，其特征为乳头真皮层的淋巴细胞性毛细血管炎。虽然局限于皮肤的白细胞破碎性血管炎常与丙型肝炎相关报道，但淋巴细胞性血管炎的报道较少。
方法
对10例色素性紫癜性皮病患者进行了临床和组织病理学研究。对所有患者进行肝炎相关检查以评估可能的关系。
结果
10例患者中，5例丙型肝炎检测呈阳性，2例乙型肝炎抗体检测呈阳性。
结论
丙型和乙型肝炎病毒可能在色素性紫癜性皮病的发病机制中起作用。需要进一步的病例对照研究来证实这一结论。
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