Morimoto Kazuyoshi, Takemoto Osamu, Wakayama Akatsuki
Department of Neurosurgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan.
Pediatr Neurosurg. 2005 Mar-Apr;41(2):84-7. doi: 10.1159/000085161.
Since its introduction, MR imaging has been easy to perform on all children with lumbosacral cutaneous stigmata, and has enabled the phenomenal refinement of spinal pathology. We investigated the overall outcomes of children with spinal lipomas at the Osaka Medical Center and Research Institute for Maternal and Child Health in Osaka, Japan. Between 1991 and 2003, 76 children with a tethered cord underwent a total of 90 surgical procedures at our institutes. Of this cohort, 67 cases had spinal lipomas. The mean age of patients at first operation for asymptomatic lipoma was 22.4 months (range: 1 month to 16 years, trim mean: 10.1 months, mode: 5 months), except 4 cases. The mean total follow-up for the cohort since the first surgical procedure was 7.2 years (trim mean: 7.9 years). Since the introduction of MR imaging, the reoperation rate for symptoms or signs in our series was 16.4% (11 cases). Regarding the 13 subsequent reoperations (2 patients had 2 operations), 3 patients were reoperated on due to multiplication of the lipomas after untethering, 3 due to urologic symptoms and 5 due to orthopedic signs. There were 2 cases who also had to undergo reoperation early due to CSF leakage. Filum and conus lipomas have similar tethering pathologies, but differ in the outcome following surgery. Filum lipomas are benign, and therefore surgery is safe and effective. Conus lipomas are more difficult to manage.
自引入以来,磁共振成像(MR成像)已易于在所有患有腰骶部皮肤体征的儿童中进行,并使脊柱病理学有了显著的细化。我们在日本大阪的大阪母婴健康医学中心和研究所调查了患有脊髓脂肪瘤的儿童的总体治疗结果。1991年至2003年期间,76例脊髓栓系患儿在我们的研究所共接受了90次手术。在这个队列中,67例患有脊髓脂肪瘤。除4例患者外,无症状脂肪瘤首次手术时患者的平均年龄为22.4个月(范围:1个月至16岁,修剪均值:10.1个月,众数:5个月)。自首次手术以来,该队列的平均总随访时间为7.2年(修剪均值:7.9年)。自引入MR成像以来,我们系列中因症状或体征进行再次手术的比例为16.4%(11例)。关于随后的13次再次手术(2例患者进行了2次手术),3例患者因松解术后脂肪瘤增多而再次手术,3例因泌尿系统症状,5例因骨科体征。有2例患者也因脑脊液漏而不得不早期进行再次手术。终丝脂肪瘤和圆锥脂肪瘤有相似的栓系病理,但手术结果不同。终丝脂肪瘤是良性的,因此手术安全有效。圆锥脂肪瘤更难处理。