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[嘌呤核苷酸代谢酶在评估免疫系统功能能力中的作用]

[Enzymes of purine nucleotide metabolism in assessment of the functional competence of the immune system].

作者信息

Tapbergenov S O, Tapbergenov T S

出版信息

Biomed Khim. 2005 Mar-Apr;51(2):199-205.

Abstract

Blood lymphocyte activities of 5'-nucleotidases, adenosine deaminase and AMP deaminase have been investigated for evaluation of immune system state of albino rats under normal conditions, immobilization stress and effect of radiation. Stress-induced reactions were characterized by changes of activities of these enzymes. However the ratios of activities 5'- nucleotidase/AMP-deaminase (coefficient A) and adenosine-deaminase/AMP-deaminase (coefficient B) were even more informative than separate analysis of these enzymes.

摘要

为评估正常条件下、固定应激和辐射影响下白化大鼠的免疫系统状态,对其血液淋巴细胞中5'-核苷酸酶、腺苷脱氨酶和AMP脱氨酶的活性进行了研究。应激诱导的反应以这些酶活性的变化为特征。然而,5'-核苷酸酶/AMP脱氨酶活性比(系数A)和腺苷脱氨酶/AMP脱氨酶活性比(系数B)比单独分析这些酶更具信息性。

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