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体重指数对医学重症监护病房患者预后的影响。

The effect of body mass index on patient outcomes in a medical ICU.

作者信息

Ray Daniel E, Matchett Stephen C, Baker Kathy, Wasser Thomas, Young Mark J

机构信息

Medical Critical Care, Lehigh Valley Hospital, Allentown, PA, USA.

出版信息

Chest. 2005 Jun;127(6):2125-31. doi: 10.1378/chest.127.6.2125.

DOI:10.1378/chest.127.6.2125
PMID:15947330
Abstract

STUDY OBJECTIVES

To examine the effect of patient body mass index (BMI) on outcome in intensive care.

DESIGN

In a prospective study, the patients were classified into groups based on the calculated BMI, as follows: BMI < 19.0 (n = 350), > or = 19.0 and < 25.0 (n = 663), > or = 25.0 and < 29.9 (n = 585), > or = 30.0 and < 40.0 (n = 396), and > or = 40.0 (n = 154). Groups were compared by age, APACHE (acute physiology and chronic health evaluation) II score, mortality, ICU length of stay (LOS), hospital LOS, number receiving ventilation, and ventilator-days. Adverse events including nosocomial pneumonia, ventilator-days per patient, failed extubations, and line-related complications were recorded.

SETTING

The study was conducted in a 9-bed medical ICU of a 650-bed tertiary care hospital.

MEASUREMENTS

Height and weight were prospectively recorded for the first ICU admission during a hospital stay.

RESULTS

Between January 1, 1997, and August 1, 2001, 2,148 of 2,806 patients admitted to the ICU had height and weight recorded. There were no differences in APACHE II score, mortality, ICU LOS, hospital LOS, number receiving ventilation, ventilator-days, average total cost, or average variable cost among the five groups. However, the severely obese patients were more frequently female and younger than those who were overweight and obese (p < 0.001). Adverse events were infrequent, but there were no differences between the obese/very obese compared with others.

CONCLUSION

BMI has minimal effects on ICU outcome after patients are admitted to a critical care unit.

摘要

研究目的

探讨患者体重指数(BMI)对重症监护结局的影响。

设计

在一项前瞻性研究中,根据计算得出的BMI将患者分为以下几组:BMI < 19.0(n = 350),≥19.0且< 25.0(n = 663),≥25.0且< 29.9(n = 585),≥30.0且< 40.0(n = 396),以及≥40.0(n = 154)。通过年龄、急性生理与慢性健康状况评估(APACHE)II评分、死亡率、重症监护病房(ICU)住院时间、医院住院时间、接受机械通气的人数以及机械通气天数对各组进行比较。记录不良事件,包括医院获得性肺炎、每位患者的机械通气天数、拔管失败以及与管路相关的并发症。

地点

该研究在一家拥有650张床位的三级医疗医院的9张床位的内科ICU中进行。

测量

前瞻性记录患者在住院期间首次入住ICU时的身高和体重。

结果

在1997年1月1日至2001年8月1日期间,入住ICU的2806例患者中有2148例记录了身高和体重。五组患者在APACHE II评分、死亡率、ICU住院时间、医院住院时间、接受机械通气的人数、机械通气天数、平均总成本或平均可变成本方面没有差异。然而,重度肥胖患者比超重和肥胖患者更常为女性且年龄更小(p < 0.001)。不良事件发生率较低,但肥胖/极肥胖患者与其他患者之间没有差异。

结论

患者入住重症监护病房后,BMI对ICU结局的影响极小。

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