Mikami Hiroshi
Course of Health Science, Graduate School of Medicine, Osaka University.
Nihon Rinsho. 2005 Jun;63(6):1096-100.
Elderly patients have much more complex QOL problems as compared with young or middle-aged patients because of their specific social and psychological circumstances, as well as their multiple organ disorders. Specifically, one should take into account, in the treatment of hypertension in the elderly with respect to QOL, the effect of antihypertensive drugs on the cognitive function and the influence on other diseases or hypertensive complications. Most of the currently used antihypertensive drugs are shown to be inert to the cognitive function. In order to maintain or improve QOL of elderly hypertensive patients, adequate drugs should be selected individually. In general, ACE inhibitors, long-acting Ca antagonists are the drugs of choice for the treatment of hypertension in the elderly with regard to QOL.
与年轻或中年患者相比，老年患者由于其特殊的社会和心理状况以及多器官疾病，生活质量问题要复杂得多。具体而言，在老年高血压患者的治疗中，就生活质量而言，应考虑降压药物对认知功能的影响以及对其他疾病或高血压并发症的影响。目前使用的大多数降压药物对认知功能无明显作用。为了维持或改善老年高血压患者的生活质量，应个体化选择合适的药物。一般来说，就生活质量而言，ACE抑制剂、长效钙拮抗剂是老年高血压治疗的首选药物。
