I期精原细胞瘤的盆腔复发：一种质疑现代放疗及随访方案的新现象。
Pelvic recurrence in stage I seminoma: a new phenomenon that questions modern protocols for radiotherapy and follow-up.
作者信息
Power Richard E, Kennedy John, Crown John, Fraser Ian, Thornhill John A
机构信息
The Adelaide and Meath Hospital Incorporating the National Children's Hospital, Tallaght, Dublin, Ireland.
出版信息
Int J Urol. 2005 Apr;12(4):378-82. doi: 10.1111/j.1442-2042.2005.01114.x.
OBJECTIVE
To highlight the increased risk for pelvic relapse in patients with stage 1 seminoma treated with adjuvant radiotherapy limited to para-aortic template alone.
PATIENTS AND METHODS
Over a four-year period, three patients presented with early pelvic recurrence after radical orchidectomy and adjuvant irradiation for stage 1 seminoma. In each case, radiotherapy had been limited to the para-aortic region with omission of the ipsilateral hemi pelvis.
RESULTS
Pelvic recurrences occurred on the ipsilateral tumor side. Durable complete remission was achieved in each case; however, treatment was complex and there was associated morbidity.
CONCLUSION
This significant incidence of pelvic recurrence questions the validity of modern radiotherapy protocol which excludes the ipsilateral pelvis from the radiation field.
目的
强调仅接受局限于主动脉旁区域模板的辅助放疗的Ⅰ期精原细胞瘤患者盆腔复发风险增加。
患者与方法
在四年期间，三名患者在根治性睾丸切除术后因Ⅰ期精原细胞瘤接受辅助放疗，随后出现早期盆腔复发。在每例病例中，放疗均局限于主动脉旁区域，未包括同侧半骨盆。
结果
盆腔复发发生在肿瘤同侧。每例均实现了持久的完全缓解；然而，治疗过程复杂且伴有并发症。
结论
盆腔复发的高发生率对将同侧骨盆排除在放疗野之外的现代放疗方案的有效性提出了质疑。
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