Yamamoto Keisuke, Yasunaga Yutaka
Urology Service, Seikeikai Hospital and Clinics, Osaka, Japan.
Int J Urol. 2005 Apr;12(4):398-400. doi: 10.1111/j.1442-2042.2005.01059.x.
This case report clarifies an adverse reaction of antiplatelet therapy which has been a standard prophylactic method for patients harboring significant risks of thromboembolic events. A 71-year-old Japanese man who had been taking aspirin tablets (81 mg) for a year presented with sudden colic pain in the left flank region. An abdominal computed tomography scan revealed a significant perirenal hematoma of the left kidney. There were no pathological kidney conditions, such as renal tumors, calculi or vascular diseases, found by magnetic resonance imaging examination. After cessation of aspirin administration followed by conservative management, the hematoma completely disappeared 6 months later. This is the first documented case of spontaneous perirenal hematoma secondary to low-dose aspirin treatment. While such unpleasant events occur extraordinarily, this should be noted as a severe risk of antiplatelet therapy.
本病例报告阐明了抗血小板治疗的一种不良反应，抗血小板治疗一直是有血栓栓塞事件重大风险患者的标准预防方法。一名71岁的日本男性，服用阿司匹林片（81毫克）一年，出现左侧胁腹区域突发绞痛。腹部计算机断层扫描显示左肾有明显的肾周血肿。磁共振成像检查未发现肾脏有诸如肾肿瘤、结石或血管疾病等病理状况。停用阿司匹林并进行保守治疗后，血肿在6个月后完全消失。这是首例有记录的低剂量阿司匹林治疗继发自发性肾周血肿的病例。虽然此类不良事件极为罕见，但应注意这是抗血小板治疗的严重风险。
