Kempf W, Kutzner H, Kettelhack N, Palmedo G, Burg G
Department of Dermatology, University Hospital Zurich, CH-8091 Zurich, Switzerland.
Br J Dermatol. 2005 Jun;152(6):1327-31. doi: 10.1111/j.1365-2133.2005.06457.x.
Paraneoplastic dermatoses are non-neoplastic skin disorders which occur in the context of an underlying malignant neoplasm. The classic paraneoplastic dermatoses are mostly associated with solid internal malignancies. They only rarely occur in the context of nodal or primary cutaneous lymphomas. Apart from these classic paraneoplastic dermatoses, there are additional skin disorders reported to occur in close association with haematological and lymphoproliferative disorders which can thus be regarded as paraneoplastic manifestations. We report for the first time two patients with pityriasis lichenoides et varioliformis acuta in association with mycosis fungoides. In addition, we review the literature on paraneoplastic dermatoses of the skin which have been described in patients with leukaemias and primary cutaneous lymphomas.
副肿瘤性皮肤病是在潜在恶性肿瘤背景下发生的非肿瘤性皮肤疾病。经典的副肿瘤性皮肤病大多与实体内部恶性肿瘤相关。它们仅极少在淋巴结或原发性皮肤淋巴瘤的背景下发生。除了这些经典的副肿瘤性皮肤病外,还有其他一些皮肤疾病据报道与血液系统和淋巴增殖性疾病密切相关,因此可被视为副肿瘤性表现。我们首次报告了两例急性痘疮样苔藓状糠疹与蕈样肉芽肿相关的病例。此外,我们回顾了关于白血病和原发性皮肤淋巴瘤患者中所描述的皮肤副肿瘤性皮肤病的文献。