Pournaras C C, Masouye I, Piletta P, Piguet V, Saurat J-H, French L E
Department of Dermatology, Geneva University Medical School, 24 rue Micheli-du-Crest, 1211 Geneva 14, Switzerland.
Br J Dermatol. 2005 Jun;152(6):1343-5. doi: 10.1111/j.1365-2133.2005.06546.x.
We report an illustrative case of an apparently healthy 38-year-old man with a past history of alopecia universalis who developed extensive, slightly pruritic, infiltrated annular verrucous lesions of the scalp, perioral, lumbar, perianal and genital areas over a 6-month period. The combination of an unusual clinical presentation, positive syphilis serology and rapid response to penicillin therapy was consistent with a diagnosis of extensive annular and verrucous late secondary syphilis. We present this case to illustrate a rare and potentially misleading clinical feature of late secondary syphilis, a disease considered to be of the past but still present in today's practice.
我们报告了一例具有代表性的病例，患者为一名38岁表面健康的男性，有全秃病史，在6个月的时间里，头皮、口周、腰部、肛周和生殖器部位出现了广泛的、轻度瘙痒的、浸润性环状疣状皮损。不寻常的临床表现、梅毒血清学阳性以及对青霉素治疗的快速反应相结合，符合广泛环状和疣状二期梅毒晚期的诊断。我们展示此病例以说明二期梅毒晚期一种罕见且可能产生误导的临床特征，这种疾病虽被认为已成为过去，但在当今临床实践中仍然存在。
