Thomas Biju B, Aramant Robert B, Sadda Srinivas R, Seiler Magdalene J
Department of Ophthalmology, Doheny Retina Institute, Doheny Eye Institute, Keck School of Medicine, University of Southern California, DVRC 402, 1355 San Pablo St., Los Angeles, CA 90033, USA.
Neurosci Lett. 2005 Sep 9;385(2):143-7. doi: 10.1016/j.neulet.2005.05.034.
Multi-unit visual responses to light intensities ranging from -6.46 to 0.81 logcd/m2 were recorded from the surface of the superior colliculus of dark-adapted normal pigmented and normal albino rats. Light sensitivity was significantly higher in albinos. The response onset latency was inversely proportional to the stimulus intensity. The progression of the stimulus intensity versus response onset latency curve showed a considerable difference between pigmented and albino rats. At low light levels, longer response onset latencies were recorded in pigmented rats than in albinos. This can be attributed to the transmission of rod-driven responses. The differences observed in the light response characteristics of albino rats may be indicative of their visual abnormalities.
在暗适应的正常有色大鼠和正常白化大鼠的上丘表面,记录了对光强度范围从-6.46至0.81 logcd/m²的多单位视觉反应。白化大鼠的光敏感性显著更高。反应起始潜伏期与刺激强度成反比。刺激强度与反应起始潜伏期曲线的进展在有色大鼠和白化大鼠之间显示出相当大的差异。在低光照水平下,有色大鼠的反应起始潜伏期比白化大鼠更长。这可归因于视杆驱动反应的传递。在白化大鼠的光反应特征中观察到的差异可能表明它们的视觉异常。