Zeredo Jorge L, Sasaki Katia M, Yozgatian Joseph H, Okada Yukio, Toda Kazuo
Division of Integrative Sensory Physiology, Department of Developmental and Reconstructive Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Jul;100(1):31-5. doi: 10.1016/j.tripleo.2004.11.012.
Anecdotal remarks suggest that incisions in oral soft tissue would be less painful if performed with laser rather than with scalpel, but such an argument remains to be scientifically validated.
Twelve rats received graded incisions to lip, gingiva, mucosa, and tongue with either a pulsed Er:YAG laser (65 mJ/pulse at 10 Hz) or a stainless steel scalpel. The amplitude of the jaw-opening reflex, as measured by the digastric muscle electromyogram, was used to quantify the nociceptive response evoked by the surgical incisions.
Except for lip, mean reflex amplitudes evoked by laser were significantly smaller (P < .05) than those evoked by scalpel in all other incision sites.
Er:YAG laser surgery may be less painful and therefore require less use of anesthesia and sedation than conventional scalpel surgery in oral soft tissue procedures.
有传闻称，口腔软组织切口若用激光而非手术刀进行，疼痛会减轻，但这一观点仍有待科学验证。
12只大鼠分别接受用脉冲式铒钇铝石榴石激光（10赫兹时65毫焦/脉冲）或不锈钢手术刀对唇部、牙龈、黏膜及舌头进行的分级切口。通过二腹肌肌电图测量的张口反射幅度，用于量化手术切口诱发的伤害性反应。
除唇部外，在所有其他切口部位，激光诱发的平均反射幅度均显著小于手术刀诱发的幅度（P < 0.05）。
在口腔软组织手术中，与传统手术刀手术相比，铒钇铝石榴石激光手术可能疼痛较轻，因此所需麻醉和镇静剂用量较少。
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