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钕钇铝石榴石激光与手术刀切口后疼痛程度的评估:一项大鼠实验研究

Evaluation of pain levels after Nd: YAG laser and scalpel incisions: an experimental study in rats.

作者信息

Kara Cankat, Süleyman Halis, Tezel Adnan, Orbak Recep, Cadirci Elif, Polat Beyzagül, Kara Ismail

机构信息

Department of Periodontology, Faculty of Dentistry, Atatürk University, Erzurum, Turkey.

出版信息

Photomed Laser Surg. 2010 Oct;28(5):635-8. doi: 10.1089/pho.2009.2639.

Abstract

BACKGROUND

Postoperative pain is a recognized sequel of periodontal surgery. The pain experience has been shown to peak in the first 24 hours following the procedure, and to decrease rapidly in subsequent days. The aim of the present study was to evaluate the pain levels following scalpel- and laser-incision of rat hind paws.

METHODS

The study was carried out on 10 albino Wistar male rats. Rats were randomly assigned to two groups: Group I (n = 5, laser surgery), or Group II (n = 5, conventional surgery with scalpel). For measuring mechanical hyperalgesia, the nociceptive threshold of the hind paw after mechanical stimulation was quantified using a Basile algesimeter. The measurements were done before the surgery and on the postoperative 1(st), 2(nd), 3(rd), and 7(th) days.

RESULTS

While the pain levels of the groups were similar before the surgical procedures, the laser-applied rats had significantly fewer nociceptive thresholds of the hind paw after mechanical stimulation compared with the scalpel-incised rats on the postoperative 1(st), 2(nd), 3(rd), and 7(th) days. Functional complications were not observed in the laser groups at three days after the surgery.

CONCLUSION

The results suggested that, for soft tissue surgery, Nd: YAG lasers have often led to shorter operative times, less pain, and fewer postoperative adverse events.

摘要

背景

术后疼痛是牙周手术公认的后遗症。疼痛体验在手术后的头24小时达到峰值,并在随后几天迅速减轻。本研究的目的是评估大鼠后爪手术刀切开和激光切开后的疼痛程度。

方法

对10只白化Wistar雄性大鼠进行研究。大鼠被随机分为两组:第一组(n = 5,激光手术),或第二组(n = 5,手术刀传统手术)。为了测量机械性痛觉过敏,使用Basile痛觉计对机械刺激后后爪的伤害性阈值进行量化。在手术前以及术后第1、2、3和7天进行测量。

结果

虽然两组在手术前的疼痛程度相似,但在术后第1、2、3和7天,与手术刀切开的大鼠相比,接受激光治疗的大鼠在机械刺激后后爪的伤害性阈值明显更低。激光组在手术后三天未观察到功能并发症。

结论

结果表明,对于软组织手术,钕:钇铝石榴石激光通常可缩短手术时间、减轻疼痛并减少术后不良事件。

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