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一群白内障手术后急性发作眼内炎的患者。

A cluster of patients with acute-onset endophthalmitis following cataract surgery.

作者信息

Chaudhry Nauman A, Lavaque Alejandro J, Scott Ingrid U, Flynn Harry W, Liggett Peter E

机构信息

New England Retina Research and Education Foundation, Hamden, Connecticut 06518, USA.

出版信息

Ophthalmic Surg Lasers Imaging. 2005 May-Jun;36(3):205-10.

PMID:15957477
Abstract

BACKGROUND AND OBJECTIVE

To describe a cluster of patients who had acute-onset endophthalmitis following cataract surgery.

PATIENTS AND METHODS

Ten patients with endophthalmitis following cataract surgery who were referred from three different anterior segment surgeons were evaluated.

RESULTS

Presenting visual acuities ranged from 20/30 to light perception (median, 20/80). All 10 eyes demonstrated vitritis, 8 of 10 eyes had hypopyon, and the remaining 2 eyes had significant anterior segment fibrin. All patients were treated with intravitreal injections of vancomycin and ceftazidime, as well as subconjunctival steroids. Vitreous cultures were positive in 2 of 10 eyes, and both grew Staphylococcus epidermidis, aqueous cultures were negative in 8 of 8 eyes (not performed in 2 patients). Follow-up ranged from 13 to 85 days (median, 37 days). All eyes showed complete resolution of inflammation and visual acuity improved to 20/40 or better in 9 eyes (90%).

CONCLUSIONS

Acute-onset endophthalmitis may occur in a cluster of patients within a short time frame. Early diagnosis and treatment may result in favorable visual outcomes.

摘要

背景与目的

描述一组白内障手术后急性发作性眼内炎患者。

患者与方法

对从三位不同眼前节外科医生处转诊来的10例白内障手术后发生眼内炎的患者进行了评估。

结果

就诊时视力范围为20/30至光感(中位数为20/80)。所有10只眼均表现为玻璃体炎,10只眼中8只眼有前房积脓,其余2只眼有明显的眼前节纤维素渗出。所有患者均接受了玻璃体腔内注射万古霉素和头孢他啶以及结膜下注射类固醇治疗。10只眼中2只眼的玻璃体培养呈阳性,均培养出表皮葡萄球菌,8只眼中8只眼的房水培养为阴性(2例未进行)。随访时间为13至85天(中位数为37天)。所有眼的炎症均完全消退,9只眼(90%)的视力提高到20/40或更好。

结论

急性发作性眼内炎可能在短时间内在一组患者中发生。早期诊断和治疗可能会带来良好的视力预后。

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