Martyr J W, Stannard K J D, Gillespie G
Department of Anaesthesia, Royal Perth Hospital, Perth, Western Australia.
Anaesth Intensive Care. 2005 Feb;33(1):64-8. doi: 10.1177/0310057X0503300110.
Intraoperative hypotension is a common and potentially deleterious event in elderly patients undergoing spinal anaesthesia for repair of hip fractures. The synergism between intrathecal opioids and local anaesthetics may allow a reduction in the dose of local anaesthetic and cause less sympathetic block and hypotension, while still maintaining adequate anaesthesia. We studied 40 elderly patients having either an insertion of a dynamic hip screw or a hemiarthroplasty and compared 9.0 mg glucose-free bupivacaine with added fentanyl 20 microg (group BF) with 11.0 m glucose-free bupivacaine alone (group B). Hypotension was defined as a fall in systolic blood pressure to less than 75% baseline or less than 90 mmHg. The incidence and frequency of hypotension in group BF were less than in group B. Similarly, falls in systolic, diastolic and mean blood pressures were all less in group BF than in group B. However, there were four failed blocks in group BF and one in group B.
术中低血压是老年髋部骨折修复患者行脊髓麻醉时常见且可能有害的事件。鞘内阿片类药物与局部麻醉药之间的协同作用可减少局部麻醉药的剂量,引起较少的交感神经阻滞和低血压,同时仍能维持充分的麻醉效果。我们研究了40例接受动力髋螺钉置入术或半髋关节置换术的老年患者,并将添加了20微克芬太尼的9.0毫克无糖布比卡因(BF组)与单独使用11.0毫克无糖布比卡因(B组)进行比较。低血压定义为收缩压降至基线的75%以下或低于90 mmHg。BF组低血压的发生率和频率低于B组。同样,BF组的收缩压、舒张压和平均血压下降幅度均小于B组。然而,BF组有4例阻滞失败,B组有1例阻滞失败。