Lemischka Ihor R
Department of Molecular Biology, Washington Road, Princeton University, Princeton, NJ 08544, USA.
Ann N Y Acad Sci. 2005 Jun;1044:132-8. doi: 10.1196/annals.1349.017.
In this essay I have attempted to provide clues relating to novel research avenues that are likely to have a broad impact on the field of stem cell biology. The specific examples, drawn from other areas, are meant to be instructive and are representative of many more similar efforts. I have suggested that the new areas of systems and synthetic biology may provide a truly deep level of understanding for many aspects of how stem cells make fate choices. Successful application of new avenues will require an integrative approach that combines experimental and computational techniques.
在本文中,我试图提供与新的研究途径相关的线索,这些途径可能会对干细胞生物学领域产生广泛影响。从其他领域选取的具体例子旨在具有启发性,并且代表了更多类似的努力。我认为,系统生物学和合成生物学的新领域可能会为干细胞如何做出命运选择的许多方面提供真正深入的理解。新途径的成功应用将需要一种结合实验和计算技术的综合方法。