Loescher Lois J, Merkle Carrie J
College of Nursing, University of Arizona, PO Box 210203, Tucson, AZ 85721-0203, USA.
J Nurs Scholarsh. 2005;37(2):111-9. doi: 10.1111/j.1547-5069.2005.00022.x.
(a) to summarize views of the interface of technology, genomic technology, and nursing; (b) provide an overview of current and emerging genomic technologies; (c) present clinical exemplars of uses of genomic technology in two disease conditions; and (d) list genomic-focused nursing research on genomic technologies.
A discussion of genomic technology in the context of nurses' views of technology, the importance of genomic technology for nurses, linking the central dogma of molecular biology to state-of-the-art tests and assays, and nurses' current use of technologies.
Human genome discoveries will continue to be an integral part of disease prevention, diagnosis, treatment, and management. These discoveries also have the potential for being integrated into nursing science. Genomic technologies are becoming a driving force in patient management, so that nurses will be unable to provide quality care without knowledge of the types of genomic technologies, the rationale for their use, and the possible sequelae that can result from genetic diagnosis or treatment. Many nurses already are using genomic technologies to conduct genomic-focused nursing research. The biobehavioral nature of much of this research further indicates the important contributions of nurses in genomics.
(a)总结技术、基因组技术与护理之间关系的观点;(b)概述当前及新兴的基因组技术;(c)展示基因组技术在两种疾病状况下应用的临床实例;(d)列举聚焦于基因组技术的护理研究。
在护士对技术的看法、基因组技术对护士的重要性、将分子生物学中心法则与最新测试和分析方法相联系以及护士当前对技术的应用等背景下讨论基因组技术。
人类基因组发现将继续成为疾病预防、诊断、治疗及管理中不可或缺的一部分。这些发现也有被整合到护理科学中的潜力。基因组技术正成为患者管理的驱动力,因此护士若不了解基因组技术的类型、使用原理以及基因诊断或治疗可能产生的后果,将无法提供高质量护理。许多护士已在使用基因组技术开展聚焦于基因组的护理研究。这类研究的生物行为学性质进一步表明了护士在基因组学中的重要贡献。