Ruangvaravate Ngamkae, Thuangtong Atiporn, Kosrirukvongs Panida, Prabhasawat Pinnita, Booranapong Wipawee, Srivannaboon Sabong
Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
J Med Assoc Thai. 2005 Mar;88(3):340-4.
To evaluate the change in intraocular pressure (IOP) measurement by Goldmann applanation tonometer after Laser in Situ Keratomileusis (LASIK) for myopia and myopic astigmatism, and to assess the correlation between the changes of lOP reading and the reduction of central corneal thickness (CCT) after LASIK in Thai patients.
Prospective correlational study.
LASIK was performed on 65 eyes of 33 patients for correction of myopia and myopic astigmatism. IOP was measured by Goldmann applanation tonometer before and 3 months after LASIK. The correlation between the change in IOP reading and the change in central corneal thickness were evaluated.
IOP reading was significantly reduced by mean of 2.9 +/- 2.5 mmHg (p = 0.0001). The authors used Pearson analysis to study the correlation between the change in IOP and the reduction of CCT. In subgroup analysis the patients were divided by degree of myopia: group 1, myopia less than -3 diopters (D) (n = 14); group 2, myopia -3 to -6 D (n = 31); group 3, myopia greater than -6 D (n = 20)). The result showed more correlation in higher myopia group (Pearson; r = 0.158 in group 3, r = -0.098 in group 2 and r = -0.102 in group 1).
Goldmann applanation tonometry underestimates the IOP in thin cornea. Variability in CCT is a potent confounder of this tonometry technique. Therefore, it has important implications for considering CCT measurement incorporated with Goldmann applanation tonometry for glaucoma diagnosis especially in myopic patients who undergo LASIK surgery.
评估近视及近视散光患者接受准分子原位角膜磨镶术(LASIK)后,使用戈德曼压平眼压计测量眼压(IOP)的变化,并评估泰国患者LASIK术后眼压读数变化与中央角膜厚度(CCT)减少之间的相关性。
前瞻性相关性研究。
对33例患者的65只眼进行LASIK手术以矫正近视和近视散光。在LASIK术前及术后3个月使用戈德曼压平眼压计测量眼压。评估眼压读数变化与中央角膜厚度变化之间的相关性。
眼压读数平均显著降低2.9±2.5 mmHg(p = 0.0001)。作者使用Pearson分析研究眼压变化与CCT减少之间的相关性。在亚组分析中,患者按近视度数分组:第1组,近视度数小于-3屈光度(D)(n = 14);第2组,近视度数-3至-6 D(n = 31);第3组,近视度数大于-6 D(n = 20)。结果显示,高度近视组的相关性更强(Pearson相关系数;第3组r = 0.158,第2组r = -0.098,第1组r = -0.102)。
戈德曼压平眼压测量法会低估薄角膜的眼压。CCT的变化是这种眼压测量技术的一个重要混杂因素。因此,在青光眼诊断中,尤其是对接受LASIK手术的近视患者,考虑将CCT测量与戈德曼压平眼压测量法结合使用具有重要意义。