Larbcharoensub Noppadol, Pongtippan Atcharaporn
Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
J Med Assoc Thai. 2005 Mar;88(3):430-5.
Kuttner tumor is a relatively uncommon disease of the salivary gland. It is also known as chronic sclerosing sialadenitis or cirrhosis of the submandibular gland. The examination of the submandibular gland characterizes clinically by a firm swelling of the gland, and histologically by progressive periductal sclerosis, dense lymphocytic infiltration with lymphoid follicle formation, reduction of the secretory gland parenchyma and fibrosis. Clinical, cytologic, histopathologic and immunohistopathologic features with briefly reviewed relevant literature describing 231 cases are discussed. The patients with the mean age of 44 years (range 13-81 years) had submandibular masses known to be present for 1 week to 55 years (mean 23.2 years). There is a slight predilection for occurrence in men. This is the first reported description of bilateral Kuttner tumor of submandibular glands in Thailand. It was initially diagnosed as a primary submandibular gland neoplasm that fine needle aspiration revealed to be chronic sialadenitis.
库特纳瘤是一种相对罕见的唾液腺疾病。它也被称为慢性硬化性涎腺炎或下颌下腺硬化症。下颌下腺检查的临床特征是腺体坚硬肿胀,组织学特征是进行性导管周围硬化、伴有淋巴滤泡形成的密集淋巴细胞浸润、分泌性腺实质减少和纤维化。本文讨论了临床、细胞学、组织病理学和免疫组织病理学特征,并简要回顾了描述231例病例的相关文献。患者平均年龄44岁(范围13 - 81岁),下颌下肿物存在时间为1周至55年(平均23.2年)。该病在男性中略有好发倾向。这是泰国首次报道的双侧下颌下腺库特纳瘤病例。最初诊断为原发性下颌下腺肿瘤,细针穿刺显示为慢性涎腺炎。