Bakken K, Landheim A S, Vaglum P
Centre for Addiction Issues, Department for Substance Abuse, Sykehuset Innlandet HF Sanderud, Postboks 68, 2312 Ottestad, Norway.
Drug Alcohol Depend. 2005 Dec 12;80(3):321-8. doi: 10.1016/j.drugalcdep.2005.04.011. Epub 2005 Jun 16.
(1) To identify clinically important differences between patients with and without social anxiety disorder (SAD) among alcohol-dependent and poly-substance-dependent patients. (2) To explore if primary SAD is a predictor of alcohol-dependency or poly-substance dependency when controlling for other Axes I and II disorders.
A consecutive sample of in- and outpatient alcohol-dependent (N = 146) and poly-substance-dependent patients (N = 114) from public treatment programmes in two catchment areas was assessed by personal interview, the Composite International Diagnostic Interview and the Millon Clinical Multiaxial Inventory.
The frequency of current SAD was 42%; SAD was significantly more frequent among poly-substance-dependent patients (51%) than among alcohol-dependent patients (34%). Patients with SAD do not represent a distinct clinical subgroup, but the occurrence of SAD is combined with the occurrence of other anxiety disorders, affective disorders and personality disorders in both substance groups. The analysis showed a trend towards primary SAD as a predictor for developing poly-substance dependency.
Patients with SAD in both substance groups exhibited more comorbid Axis I and II disorders. They may need specific psychiatric treatment for such disorders in addition to treatment for SAD. Treatment of primary SAD could be a target for preventing poly-substance dependency in young populations.
(1)确定酒精依赖和多种物质依赖患者中患有和未患有社交焦虑障碍(SAD)的患者之间临床上的重要差异。(2)在控制其他轴I和轴II障碍的情况下,探讨原发性SAD是否是酒精依赖或多种物质依赖的预测因素。
通过个人访谈、复合国际诊断访谈和米隆临床多轴问卷,对来自两个集水区公共治疗项目的酒精依赖(N = 146)和多种物质依赖门诊患者(N = 114)的连续样本进行评估。
当前SAD的发生率为42%;多种物质依赖患者中SAD的发生率(51%)显著高于酒精依赖患者(34%)。患有SAD的患者并不构成一个独特的临床亚组,但在两个物质组中,SAD的发生都与其他焦虑障碍、情感障碍和人格障碍的发生相关。分析显示原发性SAD有成为多种物质依赖发展预测因素的趋势。
两个物质组中患有SAD的患者表现出更多的轴I和轴II共病障碍。除了治疗SAD外,他们可能还需要针对这些障碍的特定精神科治疗。原发性SAD的治疗可能是预防年轻人群多种物质依赖的一个目标。