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当前对文献的理解与综述:声带瘢痕形成

Current understanding and review of the literature: vocal fold scarring.

作者信息

Hansen Jennifer K, Thibeault Susan L

机构信息

University of Utah, School of Medicine, Division of Otolaryngology-Head and Neck Surgery, Salt Lake City, UT 84132, USA.

出版信息

J Voice. 2006 Mar;20(1):110-20. doi: 10.1016/j.jvoice.2004.12.005. Epub 2005 Jun 20.

DOI:10.1016/j.jvoice.2004.12.005
PMID:15964741
Abstract

Vocal fold scarring is the greatest cause of poor voice after vocal fold injury. Scarring causes a disruption of the viscoelastic layered structure of the lamina propria, an increase in stiffness of the vibratory structure, and glottic incompetence. Current treatments for this complex condition are inconsistent and often produce suboptimal results. Research investigating this condition has dramatically increased over the last several years. The literature has been directed toward understanding vocal fold scarring at the biological level and translating this to the clinical forum. We present an up-to-date, thorough, and scholarly review of the literature in vocal fold scarring since 1996.

摘要

声带瘢痕是声带损伤后嗓音不佳的最主要原因。瘢痕形成会破坏固有层的黏弹性分层结构,增加振动结构的硬度,并导致声门闭合不全。目前针对这种复杂病症的治疗方法并不一致,且常常产生不尽人意的效果。在过去几年中,对该病症的研究显著增加。相关文献一直致力于从生物学层面理解声带瘢痕,并将其应用于临床领域。我们对自1996年以来有关声带瘢痕的文献进行了全面、深入且专业的综述。

相似文献

1
Current understanding and review of the literature: vocal fold scarring.当前对文献的理解与综述:声带瘢痕形成
J Voice. 2006 Mar;20(1):110-20. doi: 10.1016/j.jvoice.2004.12.005. Epub 2005 Jun 20.
2
Transforming growth factor β3 for the prevention of vocal fold scarring.转化生长因子 β3 预防声带瘢痕形成。
Laryngoscope. 2012 Mar;122(3):583-9. doi: 10.1002/lary.22389. Epub 2012 Jan 17.
3
Vocal fold injury following endotracheal intubation.气管插管后声带损伤。
J Laryngol Otol. 2005 Oct;119(10):825-7. doi: 10.1258/002221505774481192.
4
[Vocal fold structure and speech pathologies].[声带结构与言语病理学]
Rev Laryngol Otol Rhinol (Bord). 2005;126(5):295-300.
5
Hyaluronic acid for the treatment of vocal fold scars.用于治疗声带瘢痕的透明质酸。
Curr Opin Otolaryngol Head Neck Surg. 2010 Dec;18(6):498-502. doi: 10.1097/MOO.0b013e32833f85d1.
6
Vocal fold scarring: current concepts and management.
Otolaryngol Head Neck Surg. 1996 Nov;115(5):474-82. doi: 10.1177/019459989611500521.
7
Lamina propria replacement therapy with cultured autologous fibroblasts for vocal fold scars.采用培养的自体成纤维细胞进行固有层替代疗法治疗声带瘢痕。
Otolaryngol Head Neck Surg. 2004 Dec;131(6):864-70. doi: 10.1016/j.otohns.2004.07.010.
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Current treatment of vocal fold scarring.声带瘢痕的当前治疗方法。
Curr Opin Otolaryngol Head Neck Surg. 2005 Jun;13(3):143-7. doi: 10.1097/01.moo.0000162261.49739.b7.
9
Viscoelastic measurements after vocal fold scarring in rabbits--short-term results after hyaluronan injection.兔声带瘢痕形成后的粘弹性测量——透明质酸注射后的短期结果
Acta Otolaryngol. 2006 Jul;126(7):758-63. doi: 10.1080/00016480500470147.
10
Phonosurgery in the elderly: a review.老年患者的嗓音外科手术:综述
Ear Nose Throat J. 1999 Jul;78(7):505-9, 512.

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5-Aminolevulinic acid-mediated photodynamic therapy improves scar healing of laryngeal wounds in rats.5-氨基酮戊酸介导的光动力疗法改善大鼠喉部伤口的瘢痕愈合。
Lasers Med Sci. 2025 Sep 9;40(1):353. doi: 10.1007/s10103-025-04588-4.
2
Controlled decorin delivery from injectable microgels promotes scarless vocal fold repair.可注射微凝胶控制核心蛋白聚糖的递送促进无瘢痕声带修复。
bioRxiv. 2025 Jun 28:2025.06.25.661429. doi: 10.1101/2025.06.25.661429.
3
Controlled-Release of Dexamethasone via Light-Activated Implant for Potential Vocal Fold Scar Treatment.
通过光激活植入物实现地塞米松控释用于潜在的声带瘢痕治疗
ACS Biomater Sci Eng. 2025 Apr 14;11(4):2180-2191. doi: 10.1021/acsbiomaterials.4c02231. Epub 2025 Apr 2.
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Metformin Attenuates Vocal Fold Fibrosis via AMPK Signaling.二甲双胍通过AMPK信号通路减轻声带纤维化。
Inflammation. 2024 Oct 24. doi: 10.1007/s10753-024-02165-5.
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Immunocytochemistry assessment of vocal fold regeneration after cell-based implant in rabbits.兔基于细胞植入后的声带再生的免疫细胞化学评估
Laryngoscope Investig Otolaryngol. 2024 Oct 9;9(5):e70007. doi: 10.1002/lio2.70007. eCollection 2024 Oct.
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The Effect of Oxidative Stress on the Human Voice.氧化应激对人类嗓音的影响。
Int J Mol Sci. 2024 Feb 23;25(5):2604. doi: 10.3390/ijms25052604.
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Endotracheal tubes with dexamethasone eluting electrospun coating improve tissue mechanical function after upper airway injury.带地塞米松洗脱电纺涂层的气管内导管可改善上呼吸道损伤后的组织力学功能。
Sci Rep. 2024 Feb 3;14(1):2821. doi: 10.1038/s41598-024-53328-1.
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Options for treatment of a small glottic gap.小声门间隙的治疗选择。
Laryngoscope Investig Otolaryngol. 2023 Apr 20;8(3):720-729. doi: 10.1002/lio2.1060. eCollection 2023 Jun.
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Effects of compound betamethasone on vocal fold wound healing in rabbit model: A preliminary study.复方倍他米松对兔模型声带伤口愈合的影响:一项初步研究。
Laryngoscope Investig Otolaryngol. 2023 Feb 15;8(2):488-494. doi: 10.1002/lio2.1024. eCollection 2023 Apr.
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