Wettstein M, Lüthen R, Cohnen M, von Wrisberg F, Mödder U, Häussinger D
Gastroenterologie, Universitätsklinikum Düsseldorf.
Zentralbl Chir. 2005 Jun;130(3):246-9. doi: 10.1055/s-2005-836547.
The transjugular intrahepatic portosystemic stent shunt has replaced surgical shunt procedures as the standard therapy for complications of portal hypertension such as refractory ascites and recurrent variceal bleeding. However, reinterventions due to TIPS stenosis are necessary in 25-50 %. Major complications are the manifestation or worsening of hepatic encephalopathy. Recent studies using PTFE covered stents have shown lower stenosis rates and a trend towards prolonged survival.
经颈静脉肝内门体分流术已取代外科分流手术,成为门静脉高压并发症(如难治性腹水和复发性静脉曲张出血)的标准治疗方法。然而,25%-50%的患者因TIPS狭窄需要再次干预。主要并发症是肝性脑病的表现或加重。最近使用聚四氟乙烯覆膜支架的研究显示狭窄率较低,且有延长生存期的趋势。