Kaygusuz T Ozturk, Kaygusuz I, Kilic S S, Yalcin S, Felek S
Department of Infectious Diseases and Clinical Microbiology, Government Hospital, Elazig, Turkey.
Clin Microbiol Infect. 2005 Jul;11(7):559-63. doi: 10.1111/j.1469-0691.2005.01167.x.
This study aimed to determine the effect of acute brucellosis on the auditory system. Forty-two patients with acute brucellosis were evaluated clinically, and with serological and audiological tests, before and after treatment. Hearing threshold averages were calculated at 11 different frequencies (250-8000 Hz) of the auditory airway, and statistical analysis was performed. The average hearing thresholds were > 20 dB, with standard audiometry at 6000-8000 Hz, and < 20 dB at all other frequencies. After treatment, the average auditory threshold decreased to < 20 dB at 6000-8000 Hz (p < 0.0001). Pure-tone hearing thresholds were improved at all frequencies after treatment, with statistically significant differences at all frequencies except 12,000, 14,000 and 16 000 Hz (p < 0.05). There was no permanent hearing loss caused by acute brucellosis, and hearing thresholds were restored after treatment. It was concluded that acute brucellosis affects the auditory system, especially at high frequencies, and that patients with all forms of brucellosis should be evaluated for hearing loss.
本研究旨在确定急性布鲁氏菌病对听觉系统的影响。对42例急性布鲁氏菌病患者在治疗前后进行了临床评估以及血清学和听力学检查。计算了听觉气道11个不同频率（250 - 8000Hz）的平均听阈，并进行了统计分析。在6000 - 8000Hz的标准听力测定中，平均听阈>20dB，在所有其他频率中<20dB。治疗后，6000 - 8000Hz的平均听阈降至<20dB（p < 0.0001）。治疗后所有频率的纯音听阈均有所改善，除12000、14000和16000Hz外，所有频率均有统计学显著差异（p < 0.05）。急性布鲁氏菌病未导致永久性听力损失，治疗后听阈恢复。结论是急性布鲁氏菌病会影响听觉系统，尤其是在高频，所有形式布鲁氏菌病患者均应评估听力损失情况。
