Jäger Claudia, Jappe Uta
Universitäts-Hautklinik Heidelberg.
J Dtsch Dermatol Ges. 2005 Jul;3(7):527-9. doi: 10.1111/j.1610-0387.2005.05717.x.
During recent years demands for permanent make up and especially permanent lip liner is increasing not only in the USA but also in Germany. Adverse reactions to these products are almost unknown and not documented in literature. Declaration of contents and side effects are not required for tattoo colors, in contrast to the rules for medical treatments. Our patient developed inflammation and vesiculation within the area of tattooing three days after injection of a permanent lip liner. Treatment with steroids induced complete resolution of the lip liner-associated dermatitis. However, not only the effect of the lip liner was lost but also the natural color of her lip was partly destroyed by inflammation. Diagnostic allergy testing revealed strong delayed hypersensitivity to nickel and a mild patch test reaction to the permanent lip liner. Examination of the permanent make-up by mass spectrometry detected nickel in a concentration of 1.8 ppm. No allergic reaction could be seen when the purified red dye itself was tested. This patient with pre-existing nickel allergy developed an allergic contact dermatitis from the injection of a permanent lip liner contaminated with nickel.
近年来，不仅在美国，而且在德国，对永久性化妆尤其是永久性唇线笔的需求都在增加。这些产品的不良反应几乎不为人知，文献中也没有记载。与医疗治疗规则不同，纹身颜料不需要标明成分和副作用。我们的患者在注射永久性唇线笔三天后，纹身区域出现了炎症和水疱。使用类固醇治疗使与唇线笔相关的皮炎完全消退。然而，不仅唇线笔的效果消失了，而且她嘴唇的自然颜色也因炎症部分受损。诊断性过敏测试显示对镍有强烈的迟发性超敏反应，对永久性唇线笔有轻微的斑贴试验反应。通过质谱法对永久性化妆品进行检测，发现镍的浓度为1.8 ppm。当对纯化的红色染料本身进行测试时，未观察到过敏反应。这位已有镍过敏的患者因注射了被镍污染的永久性唇线笔而发生了过敏性接触性皮炎。
