Drillia P, Dokianakis S N, Fountoulakis M S, Kornaros M, Stamatelatou K, Lyberatos G
Department of Chemical Engineering, University of Patras, Greece.
J Hazard Mater. 2005 Jul 15;122(3):259-65. doi: 10.1016/j.jhazmat.2005.03.009. Epub 2005 Apr 8.
Sulfamethoxazole, a common antibiotic, was found to be biodegradable under aerobic conditions. The fate of sulfamethoxazole in the activated sludge process was studied using a Sequencing Batch Reactor (SBR). Aerobic biomass was acclimated to sulfamethoxazole and a series of kinetic experiments were conducted to investigate the impact of other carbon and nitrogen sources on the degradation of the antibiotic. It was found that sulfamethoxazole serves both as carbon and nitrogen source for the enriched consortium. It was degraded whenever there was a depletion of carbon or nitrogen or both in the feeding medium, while in the presence of acetate and ammonium nitrogen (alternative carbon and nitrogen sources, respectively), sulfamethoxazole remained intact.
磺胺甲恶唑是一种常见的抗生素，研究发现它在有氧条件下可生物降解。使用序批式反应器（SBR）研究了磺胺甲恶唑在活性污泥工艺中的去向。使好氧生物质适应磺胺甲恶唑，并进行了一系列动力学实验，以研究其他碳源和氮源对抗生素降解的影响。结果发现，磺胺甲恶唑对富集菌群而言既是碳源又是氮源。当进料培养基中的碳或氮或两者耗尽时，它就会被降解，而在存在乙酸盐和铵态氮（分别为替代碳源和氮源）的情况下，磺胺甲恶唑保持完整。
